Crystallization (Comment) | Organism |
---|---|
structures in complex with malonate, L-(+)-tartrate and tris | Homo sapiens |
Protein Variants | Comment | Organism |
---|---|---|
L289W | about 50% of wild-type activity with substrate myristoyl-sn-glycerol 3-phosphate | Homo sapiens |
S285W | about 50% of wild-type activity with substrate myristoyl-sn-glycerol 3-phosphate | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | no substrate: glycerol 3-phosphate. Activity increases with the length of acyl chain to a peak value on 14:0-lysophosphatidic acid. Activity gradually decreases, when the substrate length is increased above the optimal 14:0-lysophosphatidic acid | ? | - |
? | |
myristoyl-sn-glycerol3-phosphate + H2O | Homo sapiens | best substrate | myristoyl-sn-glycerol + phosphate | - |
? | |
oleoyl-sn-glycerol 3-phosphate + H2O | Homo sapiens | about 2fold the activity of stearoyl-sn-glycerol 3-phosphate | oleoyl-sn-glycerol + phosphate | - |
? | |
palmitoyl-sn-glycerol 3-phosphate + H2O | Homo sapiens | - |
palmitoyl-sn-glycerol + phosphate | - |
? | |
stearoyl-sn-glycerol-3-phosphate + H2O | Homo sapiens | - |
stearoyl-sn-glycerol + phosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q9NPH0 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | no substrate: glycerol 3-phosphate. Activity increases with the length of acyl chain to a peak value on 14:0-lysophosphatidic acid. Activity gradually decreases, when the substrate length is increased above the optimal 14:0-lysophosphatidic acid | Homo sapiens | ? | - |
? | |
myristoyl-sn-glycerol3-phosphate + H2O | best substrate | Homo sapiens | myristoyl-sn-glycerol + phosphate | - |
? | |
oleoyl-sn-glycerol 3-phosphate + H2O | about 2fold the activity of stearoyl-sn-glycerol 3-phosphate | Homo sapiens | oleoyl-sn-glycerol + phosphate | - |
? | |
palmitoyl-sn-glycerol 3-phosphate + H2O | - |
Homo sapiens | palmitoyl-sn-glycerol + phosphate | - |
? | |
stearoyl-sn-glycerol-3-phosphate + H2O | - |
Homo sapiens | stearoyl-sn-glycerol + phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Acp6 | - |
Homo sapiens |
lysophosphatidic acid phosphatase type 6 | - |
Homo sapiens |